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The study is published Oct. 13 in the New England Journal of Medicine.

it each year much lower than the assumed risk of 0.5 percent, according to the study.

By Maureen SalamonWEDNESDAY, Oct. 12 (HealthDay News) The risk of developing deadly esophageal cancer for patients with a condition known as Barrett's esophagus is significant, but not as dire as once reported, a large new Danish study suggests.

"The clinical implication is that patients with Barrett (without dysplasia) should probably only be investigated [with endoscope] the first year and hereafter no further endoscopy is necessary, unless new symptoms appear," Funch Jensen said. "Esophageal cancer has increased in incidence during the last years . if it increases very much further, the situation may change. Also, it is a possibility that we will discover other risk factors that will pinpoint a subset of patients that may benefit from surveillance."

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Analyzing records from Denmark's entire population of 5.4 million people, researchers determined that those with Barrett's esophagus a disorder often brought on by chronic reflux are about 11 times as likely as those without it to develop esophageal cancer, a substantial drop from the 30 or 40 factor increase reported in prior research.

"I don't think based on this one study alone, we can actually make policy changes and certain societal recommendations about screening," said Dr. Anthony Starpoli, a gastroenterologist at Lenox Hill Hospital in New York City. "For me, what this does is let me tell the patient, 'I think you have a little less to Nike Lebron Christmas Shoes 2017

´╗┐Esophageal Cancer Risk Less Dire for Certain Patients

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"We really don't have good guidelines in this country for screening patients with Barrett's for cancer, unless we find dysplasia," he said. "Whenever we mine a database, we're looking at numbers, not patient charts, so we don't necessarily have the full story. I think we'd need to have a similar type of study done here.".

This particularly lethal form of cancer, which grew in prevalence in the United States six fold between 1975 and 2001, occurs more often in older white men and has risk factors that include obesity and frequent heartburn. Patients with Barrett's esophagus, which sometimes produces abnormal cells, are typically monitored with frequent endoscopies, tests in which thin tubes with cameras are inserted into the esophagus and stomach to detect changes in cells lining the organs. Peter Funch Jensen, a professor of surgery at Hamlet Hospital and Clinical Institute at the University of Aarhus, said the results indicate that Barrett's esophagus patients can probably undergo fewer invasive endoscopies. Patients with low or high grade cell dysplasia abnormal cells that are often a pre cursor to cancer remain at much higher risk, however.

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Using records from the Danish Pathology Registry and the Danish Cancer Registry from 1992 through 2009, Funch Jensen and his team identified about 11,000 patients with Barrett's esophagus and analyzed their data for an average of five years. While those with the condition were found to have a much higher chance of developing esophageal cancer compared to the general population, only 0.12 percent go on to develop Nike Lebron Black And Red

The 197 cases of esophageal cancer diagnosed among all patients known to have Barrett's esophagus represented only 7.6 percent Nike Zoom Talaria Mid Flyknit of all such cases. During the same period, 2,602 new cases of esophageal cancer were diagnosed in the general population.

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